Publications

Selective excitation of hydrogen doubles the yield and improves the robustness of parahydrogen-induced polarization of low-γ nuclei

A. B. Schmidt, A. Brahms, F. Ellermann, S. Knecht, S. Berner, J. Henning, D. von Elverfeldt, R. Herges, J.-B. Hövener, A. N. Pravdivtsev, Phys. Chem. Chem. Phys. 2021, 23, 26645-26652.

DOI: 10.1039/D1CP04153C

https://pubs.rsc.org/en/content/articlelanding/2021/cp/d1cp04153c

Parahydrogen-induced polarization and spin order transfer in ethyl pyruvate at high magnetic fields

A. N. Pravdivtsev, A. Brahms, F. Ellermann, T. Stamp, R. Herges, J.-B. Hövener, Sci. Rep. 2022, 12, 19361.

DOI: 10.1038/s41598-022-22347-1

https://www.nature.com/articles/s41598-022-22347-1

Synthesis of ¹³C and ²H Labeled Vinyl Pyruvate and Hyperpolarization of Pyruvate

A. Brahms, A. N. Pravdivtsev, T. Stamp, F. Ellermann, F. D. Sönnichsen, J.-B. Hövener, R. Herges, Chem. Eur. J. 2022, 28, e202201210.

DOI: 10.1002/chem.202201210

https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.202201210

Spying on parahydrogen-induced polarization transfer using a half-tesla benchtop MRI and hyperpolarized imaging enabled by automation

F. Ellermann, A. Sirbu, A. Brahms, C. Assaf, R. Herges, J.-B. Höevner, A. N. Pravdivtsev, Nat. Commun. 2023, 14, 4774.

DOI: 10.1038/s41467-023-40539-9

https://www.nature.com/articles/s41467-023-40539-9

Exceptionally Mild and High-Yielding Synthesis of Vinyl Esters of Alpha-Ketocarboxylic Acids, Including Vinyl Pyruvate, for Parahydrogen-Enhanced Metabolic Spectroscopy and Imaging

A. Brahms, A. N. Pravdivtsev, L. Thorns, F. D. Sönnichsen, J.-B. Hövener, R. Herges, J. Org. Chem. 2023, 88, 15018-15028.

DOI: 10.1021/acs.joc.3c01461

https://pubs.acs.org/doi/10.1021/acs.joc.3c01461

Rapid in situ carbon-13 hyperpolarization and imaging of acetate and pyruvate esters without external polarizer

O. Mohiuddin, H. de Maissin, A. N. Pravdivtsev, A. Brahms, M. Herzog, L. Schröder, E. Y. Chekmenev, R. Herges, J.-B. Hövener, M. Zaitsev, D. von Elverfeldt, A. B. Schmidt, Commun. Chem. 2024, 7, 240.

DOI: 10.1038/s42004-024-01316-x

https://www.nature.com/articles/s42004-024-01316-x

Parahydrogen-Induced Polarization Relayed via Proton Exchange

K. Them, F. Ellermann, A. N. Pravdivtsev, O. G. Salnikov, I. V. Skovpin, I. V. Koptyug, R. Herges, J.-B. Hövener, J. Am. Chem. Soc. 2021, 143, 13694-13700.

DOI: 10.1021/jacs.1c05254

https://pubs.acs.org/doi/10.1021/jacs.1c05254

Nitrogen-15 dynamic nuclear polarization of nicotinamide derivatives in biocompatible solutions

J. P. Peters, A. Brahms, V. Janicaud, M. Anikeeva, E. Peschke, F. Ellermann, A. Ferrari, D. Hellmold, J. Held-Feindt, N.-m. Kim, J. Meiser, K. Aden, R. Herges, J.-B. Hövener, A. N. Pravdivtsev, Sci. Adv. 2023, 9, eadd3643.

DOI: 10.1126/sciadv.add3643

https://www.science.org/doi/10.1126/sciadv.add3643

Analysis of chemical exchange in iridium N-heterocyclic carbene complexes using heteronuclear parahydrogen-enhanced NMR

C. D. Assaf, X. Gui, O. G. Salnikov, A. Brahms, N. V. Chukanov, I. V. Skovpin, E. Y. Chekmenev, R. Herges, S. B. Duckett, I. V. Koptyug, K. Buckenmaier, R. Körber, M. Plaumann, A. A. Auer, J.-B. Hövener, A. N. Pravdivtsev, Commun. Chem. 2024, 7, 286.

DOI: 10.1038/s42004-024-01376-z

https://www.nature.com/articles/s42004-024-01376-z

Chemically induced deceleration of nuclear spin relaxation (CIDER) preserves hyperpolarization

J. P. Peters, C. Assaf, A. Brahms, K. Them, M. Gerdsen, R. Herges, J.-B. Hövener, A. N. Pravdivtsev, Sci. Adv. 2025, 11, eadx2316.

DOI: 10.1126/sciadv.adx2316

https://www.science.org/doi/10.1126/sciadv.adx2316